摘要: How to balance rice resistance and yield is an important problem for rice breeding. Plants with mutated necrotic lesion genes often have persistent broad-spectrum resistance, but spectral resistance is usually at the expense of yield. At present, many necrotic lesion mutants have been found in rice, and these genes are involved in disease resistance pathways. In this review, the characteristic, classification and molecular mechanism of necrotic lesions formation were introduced in detail. We also reviewed the molecular regulatory pathway of genes involved in rice disease resistance. We also summarized the relationship between resistance and yield of rice by using newly developed gene editing. The rational and accurate breeding strategy was discussed in order to better use molecular design technology to breed disease-resistant and high-yield varieties.